Cleotide triphosphate; PDI: Protein disulfide isomerases; PTOX: Plastidic terminal oxidase; RNA: Ribonucleic acid; ROS: Reactive oxygen species; SUS: Sucrose synthase; tAPX: Thylakoid-bound ascorbate peroxidase; TCA: Citric acid cycle; TP: Time point. Competing interests The authors declare that they have no competing interests. Authors’ contributions EC, RG, JAH, and LSH created the idea of this computational study. EC, RG, and JAH interpreted and discussed biological findings and concepts from the computationally derived final results. EC ready Figure 4. CK, HS, and EM performed all computational analyses beneath the supervision of RG and LSH and prepared all other figures and tables. All authors reviewed and approved the final manuscript. Acknowledgements This perform was supported by NSF ABI1062472.11. 12.13. 14.15.16.17.18.19. Author information 1 Division of Plant Pathology, Physiology, and Weed Science, Virginia Tech, Blacksburg, VA 24061, USA. 2Genetics, Bioinformatics and Computational Biology Plan, Virginia Tech, Blacksburg, VA 24061, USA. 3 Department of Forest Sources and Environmental Conservation, Virginia Tech, Blacksburg, VA 24061, USA. 4Department of Computer system Science, Virginia Tech, Blacksburg, VA 24061, USA. Received: two October 2012 Accepted: 19 March 2013 Published: 30 April 2013 References 1. Ruttink T, Arend M, Morreel K, Storme V, Rombauts S, Fromm J, Bhalerao RP, Boerjan W, Rohde A: A molecular timetable for apical bud formation and dormancy induction in poplar. Plant Cell 2007, 19(eight):2370?390. two. Druart N, Johansson A, Baba K, Schrader J, Sjodin A, Bhalerao RR, Resman L, Trygg J, Moritz T, Bhalerao RP: Environmental and hormonal regulation from the activity-dormancy cycle inside the cambial meristem entails stagespecific modulation of transcriptional and metabolic networks. Plant J 2007, 50(4):557?73. three. Joosen RVL, Lammers M, Balk PA, Bronnum P, Konings M, Perks M, Stattin E, Van Wordragen MF, van der Geest AHM: Correlating gene expression to physiological parameters and environmental circumstances during cold20.21. 22. 23.24.25.26.acclimation of Pinus sylvestris, identification of molecular markers using cDNA microarrays. Tree Physiol 2006, 26(ten):1297?313. Mohamed R, Wang CT, Ma C, Shevchenko O, Dye SJ, Puzey JR, Etherington E, Sheng XY, Meilan R, Strauss SH, et al: Populus CEN/TFL1 regulates initially onset of flowering, axillary meristem identity and dormancy release in Populus. Plant J 2010, 62(four):674?88. Ruonala R, Rinne PLH, Kangasjarvi J, van der Schoot C: CENL1 expression in the rib meristem affects stem elongation as well as the transition to dormancy in Populus.1638760-65-2 Chemscene Plant Cell 2008, 20(1):59?four.227783-08-6 manufacturer Gonzalez LMG, El Kayal W, Ju CJT, Allen CCG, King-Jones S, Cooke JEK: Integrated transcriptomic and proteomic profiling of white spruce stems for the duration of the transition from active growth to dormancy.PMID:26644518 Plant Cell Environ 2012, 35(four):682?01. Bohlenius H, Huang T, Charbonnel-Campaa L, Brunner AM, Jansson S, Strauss SH, Nilsson O: CO/FT regulatory module controls timing of flowering and seasonal growth cessation in trees. Science 2006, 312(5776):1040?043. Oquist G, Huner NPA: Photosynthesis of overwintering evergreen plants. Annu Rev Plant Biol 2003, 54:329?55. Scheller HV, Haldrup A: Photoinhibition of photosystem I. Planta 2005, 221(1):5?. Savitch LV, Ivanov AG, Krol M, Sprott DP, Oquist G, Huner NPA: Regulation of energy partitioning and alternative electron transport pathways through cold acclimation of lodgepole pine is oxygen dependent. Pl.